diff --git a/.changeset/dark-adults-join.md b/.changeset/dark-adults-join.md
new file mode 100644
index 0000000000..aeb6d92130
--- /dev/null
+++ b/.changeset/dark-adults-join.md
@@ -0,0 +1,5 @@
+---
+'@e2b/python-sdk': minor
+---
+
+http2 support for python sdk
diff --git a/packages/python-sdk/e2b/api/__init__.py b/packages/python-sdk/e2b/api/__init__.py
index d3dac5bb01..c30b037e96 100644
--- a/packages/python-sdk/e2b/api/__init__.py
+++ b/packages/python-sdk/e2b/api/__init__.py
@@ -132,16 +132,19 @@ def __init__(
         kwargs.pop("auth_header_name", None)
         kwargs.pop("prefix", None)
 
+        httpx_args = {
+            "event_hooks": {
+                "request": [self._log_request],
+                "response": [self._log_response],
+            },
+            "transport": transport,
+        }
+        if transport is None:
+            httpx_args["proxy"] = config.proxy
+
         super().__init__(
             base_url=config.api_url,
-            httpx_args={
-                "event_hooks": {
-                    "request": [self._log_request],
-                    "response": [self._log_response],
-                },
-                "proxy": config.proxy,
-                "transport": transport,
-            },
+            httpx_args=httpx_args,
             headers=headers,
             token=token or "",
             auth_header_name=auth_header_name,
diff --git a/packages/python-sdk/e2b/api/client_async/__init__.py b/packages/python-sdk/e2b/api/client_async/__init__.py
index 1e97a688b8..0f0c595495 100644
--- a/packages/python-sdk/e2b/api/client_async/__init__.py
+++ b/packages/python-sdk/e2b/api/client_async/__init__.py
@@ -46,6 +46,7 @@ def get_transport(config: ConnectionConfig) -> AsyncTransportWithLogger:
     transport = AsyncTransportWithLogger(
         limits=limits,
         proxy=config.proxy,
+        http2=True,
     )
     AsyncTransportWithLogger._instances[loop_id] = transport
     return transport
diff --git a/packages/python-sdk/e2b/api/client_sync/__init__.py b/packages/python-sdk/e2b/api/client_sync/__init__.py
index f3d62ca729..a2d77278be 100644
--- a/packages/python-sdk/e2b/api/client_sync/__init__.py
+++ b/packages/python-sdk/e2b/api/client_sync/__init__.py
@@ -45,6 +45,7 @@ def get_transport(config: ConnectionConfig) -> TransportWithLogger:
     transport = TransportWithLogger(
         limits=limits,
         proxy=config.proxy,
+        http2=True,
     )
     TransportWithLogger.singleton = transport
     return transport
diff --git a/packages/python-sdk/poetry.lock b/packages/python-sdk/poetry.lock
index ea9aeec13a..8a5186b132 100644
--- a/packages/python-sdk/poetry.lock
+++ b/packages/python-sdk/poetry.lock
@@ -518,6 +518,34 @@ files = [
     {file = "h11-0.16.0.tar.gz", hash = "sha256:4e35b956cf45792e4caa5885e69fba00bdbc6ffafbfa020300e549b208ee5ff1"},
 ]
 
+[[package]]
+name = "h2"
+version = "4.3.0"
+description = "Pure-Python HTTP/2 protocol implementation"
+optional = false
+python-versions = ">=3.9"
+groups = ["main"]
+files = [
+    {file = "h2-4.3.0-py3-none-any.whl", hash = "sha256:c438f029a25f7945c69e0ccf0fb951dc3f73a5f6412981daee861431b70e2bdd"},
+    {file = "h2-4.3.0.tar.gz", hash = "sha256:6c59efe4323fa18b47a632221a1888bd7fde6249819beda254aeca909f221bf1"},
+]
+
+[package.dependencies]
+hpack = ">=4.1,<5"
+hyperframe = ">=6.1,<7"
+
+[[package]]
+name = "hpack"
+version = "4.1.0"
+description = "Pure-Python HPACK header encoding"
+optional = false
+python-versions = ">=3.9"
+groups = ["main"]
+files = [
+    {file = "hpack-4.1.0-py3-none-any.whl", hash = "sha256:157ac792668d995c657d93111f46b4535ed114f0c9c8d672271bbec7eae1b496"},
+    {file = "hpack-4.1.0.tar.gz", hash = "sha256:ec5eca154f7056aa06f196a557655c5b009b382873ac8d1e66e79e87535f1dca"},
+]
+
 [[package]]
 name = "httpcore"
 version = "1.0.9"
@@ -565,6 +593,18 @@ http2 = ["h2 (>=3,<5)"]
 socks = ["socksio (==1.*)"]
 zstd = ["zstandard (>=0.18.0)"]
 
+[[package]]
+name = "hyperframe"
+version = "6.1.0"
+description = "Pure-Python HTTP/2 framing"
+optional = false
+python-versions = ">=3.9"
+groups = ["main"]
+files = [
+    {file = "hyperframe-6.1.0-py3-none-any.whl", hash = "sha256:b03380493a519fce58ea5af42e4a42317bf9bd425596f7a0835ffce80f1a42e5"},
+    {file = "hyperframe-6.1.0.tar.gz", hash = "sha256:f630908a00854a7adeabd6382b43923a4c4cd4b821fcb527e6ab9e15382a3b08"},
+]
+
 [[package]]
 name = "idna"
 version = "3.11"
@@ -1819,4 +1859,4 @@ tomli = {version = ">=2.0.1", markers = "python_version < \"3.11\""}
 [metadata]
 lock-version = "2.1"
 python-versions = "^3.10"
-content-hash = "3bbcdd84cf818e3fa11493c20ada01141c2450ad4ebdfcc5d12c4ba8dbfa86a5"
+content-hash = "10b34c02d9b97fb1fd229107629913601c669a7d81fc558d11dce61a92812743"
diff --git a/packages/python-sdk/pyproject.toml b/packages/python-sdk/pyproject.toml
index 478959a44e..f7e6a76580 100644
--- a/packages/python-sdk/pyproject.toml
+++ b/packages/python-sdk/pyproject.toml
@@ -16,6 +16,7 @@ wcmatch = "^10.1"
 protobuf = ">=4.21.0"
 httpcore = "^1.0.5"
 httpx = ">=0.27.0, <1.0.0"
+h2 = ">=4,<5"
 attrs = ">=23.2.0"
 packaging = ">=24.1"
 typing-extensions = ">=4.1.0"
diff --git a/packages/python-sdk/tests/test_api_client_transport.py b/packages/python-sdk/tests/test_api_client_transport.py
new file mode 100644
index 0000000000..ce157e1c26
--- /dev/null
+++ b/packages/python-sdk/tests/test_api_client_transport.py
@@ -0,0 +1,49 @@
+import asyncio
+
+import pytest
+
+from e2b.api.client_async import AsyncTransportWithLogger
+from e2b.api.client_async import get_api_client as get_async_api_client
+from e2b.api.client_sync import TransportWithLogger
+from e2b.api.client_sync import get_api_client as get_sync_api_client
+from e2b.connection_config import ConnectionConfig
+
+
+def test_sync_api_client_proxy_uses_explicit_transport():
+    TransportWithLogger.singleton = None
+    config = ConnectionConfig(
+        api_key="test",
+        proxy="http://127.0.0.1:9999",
+    )
+
+    api_client = get_sync_api_client(config)
+    httpx_client = api_client.get_httpx_client()
+
+    try:
+        assert "proxy" not in api_client._httpx_args
+        assert httpx_client._transport is TransportWithLogger.singleton
+        assert httpx_client._mounts == {}
+    finally:
+        httpx_client.close()
+        TransportWithLogger.singleton = None
+
+
+@pytest.mark.asyncio
+async def test_async_api_client_proxy_uses_explicit_transport():
+    AsyncTransportWithLogger._instances.clear()
+    config = ConnectionConfig(
+        api_key="test",
+        proxy="http://127.0.0.1:9999",
+    )
+
+    api_client = get_async_api_client(config)
+    httpx_client = api_client.get_async_httpx_client()
+    transport = AsyncTransportWithLogger._instances[id(asyncio.get_running_loop())]
+
+    try:
+        assert "proxy" not in api_client._httpx_args
+        assert httpx_client._transport is transport
+        assert httpx_client._mounts == {}
+    finally:
+        await httpx_client.aclose()
+        AsyncTransportWithLogger._instances.clear()